what is black seed powder good for

Ragheb, A., Attia, A., Elbarbry, F., Prasad, K., and Shoker, A. Attenuated Combined Action of Cyclosporine A and Hyperlipidemia on Atherogenesis in Rabbits by Thymoquinone. Burits, M. and Bucar, F. Antioxidant activity of Nigella sativa essential oil. Ren Fail. Vahdati-Mashhadian, N., Rakhshandeh, H., and Omidi, A. Darand M, Darabi Z, Yari Z, et al. View abstract. Vance, S. H., Benghuzzi, H., Wilson-Simpson, F., and Tucci, M. Thymoquinone supplementation and its effect on kidney tubule epithelial cells in vitro. Early research suggests that taking a combination of chanca piedra and black seed by mouth for 7 days relieves pain in people with tonsillopharyngitis. View abstract. El Mahmoudy, A., Matsuyama, H., Borgan, M. A., Shimizu, Y., El Sayed, M. G., Minamoto, N., and Takewaki, T. Thymoquinone suppresses expression of inducible nitric oxide synthase in rat macrophages. The role of black seed in the proliferation and biochemical marker levels of Hep-2 cells. Jadayil, S. A., Tukan, S. K., and Takruri, H. R. Bioavailability of iron from four different local food plants in Jordan. A., Jyothy, A., and Lei, D. K. Induction of apoptosis in HeLa cells by chloroform fraction of seed extracts of Nigella sativa. Phytother Res. Z.Allg.Mikrobiol. A., Nagi, M. N., al Gharably, N. M., Al Rikabi, A. C., and Al Bekairi, A. M. Thymoquinone protects against doxorubicin-induced cardiotoxicity without compromising its antitumor activity. The powder delivers soothing benefits and is easily digestible. Res Vet.Sci 2004;77(2):123-129. A., Tan, M., May, M., Tucci, M., and Benghuzzi, H. Comparison of potential chemotherapeutic agents, 5-fluoruracil, green tea, and thymoquinone on colon cancer cells. Kacem, R. and Meraihi, Z. Chemical composition of the fixed and volatile oils of Nigella sativa L. from Iran. Al Naggar, T. B., Gomez-Serranillos, M. P., Carretero, M. E., and Villar, A. M. Neuropharmacological activity of Nigella sativa L. extracts. Z., Zuberi, M. H., and Siddiqui, F. A. Antidiabetic activity of Nigella sativa seed extract in cultured pancreatic beta-cells, skeletal muscle cells, and adipocytes. View abstract. Early research shows that taking black seed might reduce liver damage caused by a certain drug used to treat cancer in children with a type of leukemia. View abstract. View abstract. But not all doses seem to work. A., and Al Khalaf, M. I. Thymoquinone and Nigella sativa oil protection against methionine-induced hyperhomocysteinemia in rats. Immunopharmacology 1995;30:147-55. View abstract. Chakravarty N. Inhibition of histamine release from mast cells by nigellone. Boskabady, M. H., Mohsenpoor, N., and Takaloo, L. Antiasthmatic effect of Nigella sativa in airways of asthmatic patients. Ann Saudi Med 2017;37:56-63. Soleymani S, Zargaran A, Farzaei MH, et al. Razmpoosh E, Safi S, Abdollahi N, et al. Mourad, A. K., Zaghloul, O. Eur.J Pharmacol. Mahmoud, M. R., El Abhar, H. S., and Saleh, S. The effect of Nigella sativa oil against the liver damage induced by Schistosoma mansoni infection in mice. View abstract. Toama, M. A., El Alfy, T. S., and El Fatatry, H. M. Antimicrobial activity of the volatile oil of Nigella sativa Linneaus seeds. Archeological studies report that black cumin seed seeds have been found in several sites from ancient Egypt, including … A. Nigellidine-4-O-sulfite, the first sulfated indazole-type alkaloid from the seeds of Nigella sativa. J Carcinog. Therapeutic value of black seed oil in methotrexate hepatotoxicity in Egyptian children with acute lymphoblastic leukemia. Therapie 2000;55(3):379-382. 2004;279(1):685-691. View abstract. Pak.J Biol.Sci 12-1-2007;10(23):4319-4322. Role of Nigella sativa and a number of its antioxidant constituents towards azoxymethane-induced genotoxic effects and colon cancer in rats. View abstract. View abstract. Phytochemistry 2009;70(4):517-522. Black seed powder mixed in honey: actually tastes great Black seed also helps as an analgesic, is good for weight loss, is anti-inflammatory and has many other great properties including stimulating the liver, helping elasticity of blood vessels, and stimulating tumor cell death while inhibiting kidney cell death. Biomed.Sci.Instrum. Early research shows that applying a cream containing black seed oil to the skin for 6 months can improve skin color in some people with vitiligo. Khan, N. and Sultana, S. Inhibition of two stage renal carcinogenesis, oxidative damage and hyperproliferative response by Nigella sativa. J Physiol Pharmacol. 2008;20(3):72-74. Aqel MB. View abstract. Planta Med 2001;67(1):29-32. Fundam.Clin Pharmacol. View abstract. 1993;24(5):1123-1131. Early research suggests that taking black seed oil by mouth might improve symptoms in people with itchy and inflamed skin. Gali-Muhtasib, H., Roessner, A., and Schneider-Stock, R. Thymoquinone: a promising anti-cancer drug from natural sources. View abstract. 2001;76(1):45-48. Phytother.Res 2009;23(9):1295-1298. A., Mostafa, A. A., Mostafa, A. Chaubey, M. K. Fumigant toxicity of essential oils from some common spices against pulse beetle, Callosobruchus chinensis (Coleoptera: Bruchidae). Effect of thymoquinone on ethylene glycol-induced kidney calculi in rats. Nickavar, B., Mojab, F., Javidnia, K., and Amoli, M. A. Taking black seed might improve some but not all measures of thyroid function in people with a disease called Hashimoto's thyroiditis. Heart damage caused by the drug doxorubicin. An investigation on LD50 and subacute hepatic toxicity of Nigella sativa seed extracts in mice. Toxicology 3-7-2000;143(3):219-226. 1965;48:Suppl-202. Iranian Journal of Diabetes & Lipid Disorders (IRANIAN J DIABETES LIPID DISORD) 2007;6(3):E29. Kanter, M. Protective effects of Nigella sativa on the neuronal injury in frontal cortex and brain stem after chronic toluene exposure. Gilani, A. H., Aziz, N., Khurram, I. M., Chaudhary, K. S., and Iqbal, A. Bronchodilator, spasmolytic and calcium antagonist activities of Nigella sativa seeds (Kalonji): a traditional herbal product with multiple medicinal uses. 2006;6(7):1135-1142. View abstract. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. The effect of thymoquinone, the main constituent of Nigella sativa on tracheal responsiveness and white blood cell count in lung lavage of sensitized guinea pigs. Womack, K., Anderson, M., Tucci, M., Hamadain, E., and Benghuzzi, H. Evaluation of bioflavonoids as potential chemotherapeutic agents. Khan, M. A., Ashfaq, M. K., Zuberi, H. S., Mahmood, M. S., and Gilani, A. H. The in vivo antifungal activity of the aqueous extract from Nigella sativa seeds. View abstract. High cholesterol. Arzneimittelforschung. 1965;15(10):1227-1229. The fiber in flaxseed is found primarily in the seed coat. The effects of isolated antioxidants from black seed on the cellular metabolism of A549 cells. Mansour, M. A., Ginawi, O. T., El Hadiyah, T., El Khatib, A. S., Al Shabanah, O. Contact Dermatitis 1997;36(5):268-269. Pak.J Pharm.Sci 2009;22(2):139-144. There is some scientific evidence to suggest that black seed might help boost the immune system, fight cancer, prevent pregnancy, and lessen allergic reactions by acting as an antihistamine, but there isn't enough information in humans yet. Hosseinzadeh, H., Parvardeh, S., Asl, M. N., Sadeghnia, H. R., and Ziaee, T. Effect of thymoquinone and Nigella sativa seeds oil on lipid peroxidation level during global cerebral ischemia-reperfusion injury in rat hippocampus. Black seed oil ointment - A new approach for the treatment of atopic dermatitis? J Altern.Complement Med 2009;15(6):639-644. However, not all research agrees. Kaleem, M., Kirmani, D., Asif, M., Ahmed, Q., and Bano, B. Biochemical effects of Nigella sativa L seeds in diabetic rats. Black seed, when taken by mouth in small quantities, such as a flavoring for foods, is LIKELY SAFE for most people. But that the black seeds work, it is a fact already proven by science and multiple studies. Research shows that taking black seed by mouth along with asthma medicines can improve coughing, wheezing, and lung function in some people with asthma. View abstract. View abstract. But it doesn't improve overall survival. Indigestion (dyspepsia). Scientia Pharmaceutica (Austria) 2006;74:159-173. View abstract. View abstract. Pregnant or lactating women – Talk to your doctor before using black seed oil. 3. Badary, O. Zaoui, A., Cherrah, Y., Alaoui, K., Mahassine, N., Amarouch, H., and Hassar, M. Effects of Nigella sativa fixed oil on blood homeostasis in rat. Obesity. Post-coital contraceptive efficacy of the seeds of Black seed in rats. Wilson-Simpson, F., Vance, S., and Benghuzzi, H. Physiological responses of ES-2 ovarian cell line following administration of epigallocatechin-3-gallate (EGCG), thymoquinone (TQ), and selenium (SE). 11-14-2005;11(42):6662-6666. The effect of Nigella sativa L. supplementation on serum C-reactive protein: a systematic review and meta-analysis of randomized controlled trials. Am.J Nephrol. Effects of Nigella sativa seeds on intestinal smooth muscle. Kanter, M., Demir, H., Karakaya, C., and Ozbek, H. Gastroprotective activity of Nigella sativa L oil and its constituent, thymoquinone against acute alcohol-induced gastric mucosal injury in rats. Today, black seed is used for treating digestive tract conditions including gas, colic, diarrhea, dysentery, constipation, and hemorrhoids. El Obeid, A., Hassib, A., Ponten, F., and Westermark, B. View abstract. View abstract. The seeds can also flavor curries, pickles, and bread in a similar way to cumin or oregano. Phytother.Res 2006;20(10):869-871. A. Thymoquinone ameliorates renal oxidative damage and proliferative response induced by mercuric chloride in rats. View abstract. Biomed.Sci.Instrum. The effect of nigella sativa oil on the prevention of phlebitis induced by chemotherapy: a clinical trial. In ancient texts and historical documents black cumin seed is noted for its therapeutic attributes and ability to support the body in its own natural healing processes. Sethi, G., Ahn, K. S., and Aggarwal, B. Phytother.Res 2003;17(2):183-186. Exp.Lung Res 2008;34(4):183-194. Bamosa, A. O., Ali, B. Antioxidant Activity and Hepatoprotective Potential of Black Seed, Honey and Silymarin on Experimental Liver Injuries Induced by CCl4 in Rats. Effect of Nigella sativa oil extracts on inflammatory and oxidative stress markers in Behcet's disease: A randomized, double-blind, placebo-controlled clinical trial. A., El Maraghy, S. S., and Eman, Mostafa M. Natural occurrence of mycotoxins in different spices in Egypt. View abstract. J Exp.Clin Cancer Res 2002;21(3):341-346. Parvardeh S and et al. 2-25-2004;4:3. Black seed might lower blood sugar in some people. Effect of Nigella sativa on blood hemostatic function in rats. Sayed, A. Neurochem.Res 2008;33(1):87-96. Effect of Nigella sativa oil versus metformin on glycemic control and biochemical parameters of newly diagnosed type 2 diabetes mellitus patients. Black seed is sometimes used in combination with cysteine, vitamin E, and saffron to ease the side effects of a chemotherapy drug called cisplatin. Int J Oncol. Pak.J Pharm.Sci 1989;2(1):25-28. A., Daba, M. H., Asiri, Y. Khadr ME and et al. El Fatatry, H. M. Isolation and structure assignment of an antimicrobial principle from the volatile oil of Nigella sativa L. seeds. 2000;72(1-2):299-304. Int J Biochem Cell Biol. Neurochem.Res 2008;33(1):87-96. Kruk, I., Michalska, T., Lichszteld, K., Kladna, A., and Aboul-Enein, H. Y. 8-14-2006;543(1-3):40-47. 2008;20(2):118-124. Egypt J Immunol. View abstract. View abstract. Early research shows that using a nasal spray containing black seed oil can reduce dryness, blockage, and crusting of the nostrils in elderly patients with nasal irritation. A., Al Sawaf, H. A., Al Sohaibani, M. O., and Al Bekairi, A. M. Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity. View abstract. Chemosphere 2000;41(7):1059-1064. Apoptosis. Mol.Cancer Ther 2008;7(7):1789-1796. Attia, A., Ragheb, A., Sylwestrowicz, T., and Shoker, A. Attenuation of high cholesterol-induced oxidative stress in rabbit liver by thymoquinone. You can take black seed oil while on conventional treatments such as chemotherapy and radiation but we highly recommend you go the natural route as research has shown that chemo causes secondary cancers and has a 2.1 percent survival rate past five years. Islam, S. K., Ahsan, M., Hassan, C. M., and Malek, M. A. Antifungal activities of the oils of Nigella sativa seeds. Complement Ther Med. Mansour, M. A., Nagi, M. N., El Khatib, A. S., and Al Bekairi, A. M. Effects of thymoquinone on antioxidant enzyme activities, lipid peroxidation and DT-diaphorase in different tissues of mice: a possible mechanism of action. Ali, Z., Ferreira, D., Carvalho, P., Avery, M. A., and Khan, I. The effect of Nigella sativa oil against Aspiculuris tetraptera and Hymenolepis nana in naturally infected mice. Some research shows that taking black seed oil or powder might improve weight loss by a small amount in people who are obese or overweight. Phytother.Res. 2008;46(12):805-810. Akhondian JAV and et al. There isn't enough information to know if larger, medicinal quantities are safe. View abstract. The appropriate dose of black seed depends on several factors such as the user's age, health, and several other conditions. A pilot study on the effects of Nigella sativa seeds aqueous extract on paediatric intractable seizures. Haq, A., Lobo, P. I., Al Tufail, M., Rama, N. R., and Al Sedairy, S. T. Immunomodulatory effect of Nigella sativa proteins fractionated by ion exchange chromatography. View abstract. Food Chem.Toxicol. Epileptic Disord 2013;15:295-301. Meral, I. and Kanter, M. Effects of Nigella sativa L. and Urtica dioica L. on selected mineral status and hematological values in CCl4-treated rats. View abstract. Influence of simulated digestion in various pH conditions on antioxidant activity and composition of extracts from selected spices. View abstract. Repeated administration of Nigella sativa decreases 5-HT turnover and produces anxiolytic effects in rats. Comparative evaluation of nigella sativa (Kalonji) and simvastatin for the treatment of hyperlipidemia and in the induction of hepatotoxicity. Biol.Trace Elem.Res 2005;107(3):277-287. Badary, O. Proximate analysis and fatty acid composition of Nigella sativa (Kalonji) seed oil growing in Pakistan. Effect of Nigella sativa (N. sativa L.) and oxidative stress on the survival pattern of MCF-7 breast cancer cells. Phytother.Res 2007;21(9):898-899. The possible prophylactic effect of Nigella sativa seed aqueous extract on respiratory symptoms and pulmonary function tests on chemical war victims: a randomized, double-blind, placebo-controlled trial. Black seed — also known by its scientific name, Nigella sativa — is a small seed that comes from a flowering plant by the same name and is found in certain areas of Southeast Asia. 2010;92(2):395-412. View abstract. 2003;17(4):299-305. Yakugaku Zasshi 2006;126(4):301-305. View abstract. Digestive problems including intestinal gas and diarrhea. The presence of a patent doesn't mean black seed has been shown to be effective for this use. 2009;6(8):1440-1447. Phytomedicine 2005;12(3):194-202. Black seed might cause sleepiness and drowsiness. Kanter, M., Coskun, O., and Uysal, H. The antioxidative and antihistaminic effect of Nigella sativa and its major constituent, thymoquinone on ethanol-induced gastric mucosal damage. Biomed.Sci Instrum. Yildiz, F., Coban, S., Terzi, A., Savas, M., Bitiren, M., Celik, H., and Aksoy, N. Protective effects of Nigella sativa against ischemia-reperfusion injury of kidneys. El Wakil, S. S. Evaluation of the in vitro effect of Nigella sativa aqueous extract on Blastocystis hominis isolates. 2001;110(3-4):239-251. Houghton PJ, Zarka R, de las Heras B, Hoult JR. A skin disorder that causes white patches to develop on the skin (vitiligo). Acta Microbiol.Pol. 2004;94(2-3):251-259. Mutat.Res 4-26-2002;516(1-2):11-17. 2003;22(4):193-203. The influence of Nigella sativa for asthma control: A meta-analysis. Some sedative medications include Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others. Shafei, M. N., Boskabady, M. H., and Parsaee, H. Effect of aqueous extract from Nigella sativa L. on guinea pig isolated heart. The effect of thymol and its derivatives on reactions generating reactive oxygen species. Al Ghamdi, M. S. The anti-inflammatory, analgesic and antipyretic activity of Nigella sativa. View abstract. View abstract. A., Tucci, M., and Benghuzzi, H. A comparison of 5-fluorouracil and natural chemotherapeutic agents, EGCG and thymoquinone, delivered by sustained drug delivery on colon cancer cells. Bamosa, A. O., Ali, B. 1999;54(4):285-294. 2006;82(6):1691-1696. El Mahmoudy, A., Shimizu, Y., Shiina, T., Matsuyama, H., El Sayed, M., and Takewaki, T. Successful abrogation by thymoquinone against induction of diabetes mellitus with streptozotocin via nitric oxide inhibitory mechanism. View abstract. Biomed.Sci Instrum. Fawzia, Al Charchafchi, M. R., Al Shuhumi, H., Al Meselhy, S., Al Busadi, M., and Al Shuhumi, H. Biological activity of seed aqueous extract of Nigella sativa (L.) on germination and seedling growth of Vigna radiata (L.). 2007;13(12):CR555-CR559. View abstract. A. Thymoquinone enhances the activities of enzymes related to energy metabolism in peripheral leukocytes of diabetic rats. 2009;4(1):43-46. View abstract. Fundam Clin Pharmacol 2008;22:447-52. © 2005 - 2019 WebMD LLC. View abstract. J Ethnopharmacol 1991;31:283-9. Arslan E, Sayin S, Demirbas S, et al. Mehta, B. K., Mehta, P., and Gupta, M. A new naturally acetylated triterpene saponin from Nigella sativa. J Ethnopharmacol. Possible hepatotoxicity of Nigella sativa seeds and Dregea volubilis leaves. View abstract. Haqqaq EG, Abou-Moustafa MA, Boucher W, Theoharides TC. View abstract.

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